Science concept – Star Warz http://star-warz.net/ Wed, 29 Jun 2022 02:24:02 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 https://star-warz.net/wp-content/uploads/2021/06/icon-2021-06-23T234539.702-150x150.png Science concept – Star Warz http://star-warz.net/ 32 32 Pilbara will become the largest renewable energy center in the world https://star-warz.net/pilbara-will-become-the-largest-renewable-energy-center-in-the-world/ Tue, 28 Jun 2022 21:30:00 +0000 https://star-warz.net/pilbara-will-become-the-largest-renewable-energy-center-in-the-world/ Great ideas are easy. Finding the big bucks and big names to back them is not. But a long-term plan to turn WA’s Pilbara into the world’s largest renewable energy center has just taken a giant step. It’s not just about exporting. It’s not just about mining. Regional communities like Karratha and Broome across the […]]]>

Great ideas are easy. Finding the big bucks and big names to back them is not. But a long-term plan to turn WA’s Pilbara into the world’s largest renewable energy center has just taken a giant step.

It’s not just about exporting. It’s not just about mining.

Regional communities like Karratha and Broome across the Pilbara are poised to become the heart of green industry in Australia. And a company town will be built to house the people employed by the new project – replacing the existing model of a fly-in workforce with a semi-permanent residence.

Hedland
The Asian Renewable Energy Hub (AREH), as well as surrounding towns and mining sites that stand to benefit from its construction. Credit: BP
Hedland
A proposed development of the AREH site of 668,100 ha. Credit: InterContinental Energy

The idea of ​​an Asian Renewable Energy Hub (AREH) was born in 2014. The initial concept was to export electricity generated from solar energy to Indonesia and Singapore via sub-cables. high voltage sailors.

This idea was not entirely rejected.


Also read: Steelmaking is critical – and an extremely serious carbon problem.


But a shift prompted international energy giant BP to buy a 40.5% stake in the project and assume responsibility as operator.

The objective is still to produce up to 26 GW of renewable electricity each year from a mix of wind and solar. This equates to a third of all electricity generated in Australia in 2020.

But it’s going to be used to generate about 1.6 million tons of hydrogen, or 9 million tons of ammonia, every year. And in the process, it is hoped to eliminate 17 million tons of annual carbon emissions.

The objective is still to produce up to 26 GW of renewable electricity each year from a mix of wind and solar.

Existing rail and maritime infrastructure, established to serve the region’s mining industry, will also benefit from the new energy hub as part of a plan to accelerate the transition to a hydrogen-based economy across the Pilbara.

This will replace diesel, petrol and gas as the main drivers of industry.

And at least 3 GW of the new green electricity will be reserved for use in the Pilbara itself.

“Providing low-cost green energy to communities and industry in Pilbara would create thousands of jobs and catalyze significant new manufacturing and mineral processing opportunities for WA,” said the Regional Development Minister of the state, Alannah MacTiernan.

“A project of this scale will require new supply chain facilities for the manufacturing and assembly of wind, solar and hydrogen generation equipment, which will create new, high-value local jobs.”

The idea is that reliable access to such cheap, clean energy will boost mineral processing in the Pilbara itself – and attract other energy-hungry manufacturers to the area.

AREH is a 668,100 ha site between Port Hedland and Broome.

BP hopes this will help it secure a 10% global share of the hydrogen market.

What makes this particular site so appealing is that it tends to be windy at night and sunny during the day, balancing peaks and troughs in power generation.

Approval has been granted for up to 1,743 wind turbines and 37 55 MW solar panels to be built within its boundaries. Four high-voltage cables will transport part of this electricity to the sea, and 37 substations will distribute the flow.

A desalination plant will treat seawater for the hydrogen and ammonia production facilities.


Also read: Fortescue Metals Group has found a fast train to a greener future


Construction work is expected to begin next year. The first electricity should start flowing in 2025.

Once fully developed, BP hopes it will help it secure a 10% global share of the hydrogen market.

“AREH is poised to become one of the largest renewable and green hydrogen energy centers in the world and can make a significant contribution to the energy transition of Australia and the wider Asia-Pacific region” , said Anja-Isabel Dotzenrath, executive vice president of BP. “It will also serve as a long-term contributor to clean energy security in the Asia-Pacific region, helping countries like South Korea and Japan to decarbonize.”


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An Evening with Richard Dawkins https://star-warz.net/an-evening-with-richard-dawkins/ Mon, 27 Jun 2022 01:31:13 +0000 https://star-warz.net/an-evening-with-richard-dawkins/ The controversial evolutionary biologist – who coined the term ‘meme’ – is touring Australia and New Zealand for a series of unscripted conversations about religion, science and the importance of reason. A lot has happened in the world since Richard Dawkins last visited Australia. The best-selling British author and evolutionary biologist toured here in 2018, […]]]>

The controversial evolutionary biologist – who coined the term ‘meme’ – is touring Australia and New Zealand for a series of unscripted conversations about religion, science and the importance of reason.

A lot has happened in the world since Richard Dawkins last visited Australia. The best-selling British author and evolutionary biologist toured here in 2018, about a year before the spread of Covid skepticism and conspiratorial thinking began to threaten popular faith in scientists and scientific reasoning .

It’s a topic the prominent atheist will most likely touch on when he comes here for a series of unscripted conversations, where he’ll discuss science, religion and more.

Dawkins is one of the most influential scientists of our time. He wrote a number of books, including his highly acclaimed 1976 title, The selfish gene, which held that natural selection operates at the genetic level rather than at the level of the individual or species. It was in this book that Dawkins introduced the concept of “memes”.

He is also famous for his 2006 The illusion of Godwhere he discussed the benefits of atheism for society and the individual.

While he won millions of followers for his impassioned arguments about the vital importance of science, reason and critical thinking, and won awards for his contributions to communicating scientific concepts to the public, Dawkins also courted controversy.

He recently came under fire for his comments on Twitter about trans people, and in 2014 he raised his eyebrows when he suggested it was immoral not to abort a fetus with Down syndrome.

Her six-city tour kicks off in Melbourne before heading to Sydney, Perth and Brisbane, then ending in New Zealand. Tickets go on sale Thursday, June 30 at 10 a.m. local time.

tegdainty.com

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Inside Indus’ latest episode reveals how the game’s concept is tied to a futuristic India https://star-warz.net/inside-indus-latest-episode-reveals-how-the-games-concept-is-tied-to-a-futuristic-india/ Sat, 25 Jun 2022 08:42:48 +0000 https://star-warz.net/inside-indus-latest-episode-reveals-how-the-games-concept-is-tied-to-a-futuristic-india/ At the beginning of this year in January, SuperGaming announcement Industry: Battle Royale. A made in India battle royale for the world that will be available for Mobile, PC and Console platforms. Given India’s highly lucrative and rapidly changing game industry, this is a big step for the future. Now the country has a battle […]]]>

At the beginning of this year in January, SuperGaming announcement Industry: Battle Royale. A made in India battle royale for the world that will be available for Mobile, PC and Console platforms. Given India’s highly lucrative and rapidly changing game industry, this is a big step for the future. Now the country has a battle royale game of its own, and what’s an added bonus is that the game focuses on showcasing the world with a futuristic version of india. Since the announcement, Indus has been making headlines for various aspects that have been unique to the game. And now, in the latest episode of Inside the Industhe developers revealed all about the concept of Industry: Battle Royale.

Indus: Battle Royale is inspired by the great Indus Valley Civilization and the concept is Indo-Futurism

Indus is a battle royale game that will be available for PC, mobile, and console platforms around the world. Indus developers said that “Indus is a battle royale made in India for the world for mobile, PC and consoles with a 2022 release date. It is developed with the aim of bringing our take on Indian culture with a futuristic twist for gamers around the world .

In the latest episode of Inside Indus, CEO RobyIndus writers, Ankush and Rishi talked about the main underlying theme of the game which is called Indo-Futurism. In the video, the speakers also talk about the theme’s inspiration derived from the great Indus Valley Civilization. They also talked about what could have happened to the Indus Valley Civilization? What if they had traveled to the future?

Keeping this as the basic idea, the team brainstormed many ideas to make the game’s story as futuristic as possible and ended up drawing inspiration from the concept of afro-futurism that was first introduced. in the movie. Black Panther with the interpretation of Wakanda, a futuristic city with themes that combine Africa’s rich heritage with a hopeful future. This gave rise to the main theme of Indus, Indo-Futurism.

The game is set in the year 2500 and shows the future of India

Indus is based in the year 2500 and unlike any other battle royale game, Indus is not in a destroyed or dark state. It is set in an optimistic vision of India in the future and shows what could have been and what can still be. It gives players a unique reason to come back to the game again and again. Indo-Futurism also highlights those underrepresented regions of India that deserve local and global recognition.

Through Indo-futurism, the development team aims to set a bar for Indian games in the global gaming market. So far, we haven’t had much success in this task, but with Indus, the team hopes to represent the Indian vision of science fiction rooted in our culture, as with Godzilla from Japan or the Fallout series from United States. The fundamental pillars of Indo-Futurism are:

  1. Indian
  2. Futurism
  3. Culture
  4. Science
  5. Optimism

While the theme of the game explains the first two fundamental pillars, the others are extremely important considering science fiction. Science fiction over the years has been regularly associated with dystopian-style stories. However, with Indus, the development team plans to shift the narrative towards hope and optimism.

Experience modern weapons and futuristic battle royale gameplay

As the Indus is a futuristic world that has eliminated major societal issues with citizens that have a deeper understanding of their role in the world that emphasizes the use of technology for the betterment of the planet while remaining true to our roots and happily representing Indian mythology and elements of our culture such as arts and traditions.

Picture via SuperGaming

Despite all the Indianness involved, the game still has lethal modern weapons, mechanics, and gameplay that matches the current feel of the Battle Royale genre. The main goal of the team is to present users with an example of what Indian science fiction can do and to create a universe in which players and their friends can explore where they have stories to tell from Virlok.

What do you think of the concept of Indus: Battle Royale revealed in the episode Inside Indus? Let us know in the comments below!

For more mobile gaming news and updates, join our whatsapp group, Telegram Group, Where Discord Server. Also, follow us on Google News, instagram, and Twitter for quick updates.

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Beavis and Butt-Head do the Universe Review https://star-warz.net/beavis-and-butt-head-do-the-universe-review/ Wed, 22 Jun 2022 17:30:16 +0000 https://star-warz.net/beavis-and-butt-head-do-the-universe-review/ Beavis and Butt-Head Do the Universe will air on Paramount+ on June 23, 2022. It’s been over a decade since we’ve heard of Beavis and Butt-Head, the slacker teenagers who brought us some of the best lowbrow humor ’90s TV had to offer. After the show ended its original run with a seventh season and […]]]>

Beavis and Butt-Head Do the Universe will air on Paramount+ on June 23, 2022.

It’s been over a decade since we’ve heard of Beavis and Butt-Head, the slacker teenagers who brought us some of the best lowbrow humor ’90s TV had to offer. After the show ended its original run with a seventh season and then had a short-lived reboot in 2011, these two big-headed but small-brained scoundrels are back for a sequel to the first Beavis and Butt-Head Flick, Beavis and Butt-Head Do America. It’s also a sneaky way to bring these 90s pop culture icons into the future, with a new revival of the series at Paramount+ coming in the pipeline. It’s like they’ve never left, as they settle into a short but sweet 1.5-hour adventure that sees them grow into full-fledged astronauts and meet their smarter future selves – ​all in the name of scoring.

Worried that something has changed about them over the past decade? Do not be. Delinquent dumbbells are just as dumb as ever. In fact, when we catch up with them, it’s still 1998, and Butt-Head (Mike Judge) is kicking Beavis (also a judge) in the ‘nads at the school science fair to see how much long he can endure before fainting. The “experiment” quickly ends when the whole science fair goes up in flames, an accident that lands the couple in front of a judge who takes pity on them for being the “at-risk kids” that they are. The verdict? Guilty. The punishment? Space camp.

In a hilariously terrible misunderstanding, Serena Ryan (Andrea Savage), captain of the space shuttle Endeavour, employs Beavis and Butt-Head at NASA to do a job only they can do, involving a visual gag that will have you bursting with laugh immediately. Our dumb duo think it’s an elaborate production to get them to sleep with her, of course. Cue a sophomore frolicking through a literal black hole and back where Beavis and Butt-Head find themselves searching for Serena in an attempt to get laid, all the way to the future, circa 2022. Yes , it’s a fish-out-of-water time-travel comedy. Fortunately, it doesn’t take itself too seriously or rely too much on the same tired jokes you’d expect from other animated films of this ilk. It’s refreshing and original in that regard, and does a great job of introducing Beavis and Butt-Head to a new generation, both literally and as part of the story.

There’s no shortage of the same silly gags and college sex jokes you’d see on the show. Neither Beavis nor Butt-Head can understand even the most basic concepts. But Beavis isn’t just about dating a woman. He also has a soft spot, as evidenced by the fact that he mistakes Siri (yes, Siri’s real voice, Susan Bennett) on an iPhone for Serena. That’s real love: He dives into a very full Port-A-Potty with “all the shit” to get “Serena” back, because he can’t lose her. And there’s a heartbreaking moment where the boys confuse the concept of white privilege with permission to steal anything without repercussions. Beavis even has a moment to shine where he busts out his alter ego Cornholio once again, demanding that a prison provide its inmates with more “TP for their bungs.”

If you’ve been a fan since the very beginning, you’ll have a great time watching these two idiots.


Visually, it may be the best Beavis and Butt-Head have ever seen. Titmouse, Inc. is on deck (picking up Season 8’s Film Roman) for stunning environments and realistic characters more evocative of the studio’s work on Metalocalypse and Superjail! than what we are used to for the series. The improved fidelity also gives a more obviously modern take on Beavis and Butt-Head. And the doubles? Mike Judge certainly hasn’t lost his touch as the titular characters, though the film has heavyweights like Gary Cole, Tig Notaro, and Jimmy O. Yang fleshing out the rest of the cast.

Let’s be clear: this is childish and sophomoric stuff. If you’ve been a fan since the very beginning, you’ll have a great time watching these two idiots. This is Beavis and Butt-Head in their purest distilled form. We don’t get much of that lopsided silliness anymore, and that kind of ridiculousness can heal the soul a bit if you let it take over. If you like the series, you will also like the movie. And that’s good, because with a whole new series on the way, you’ll want to be ready for Beavis and Butt-Head overload.

All exclusive movies and TV series are coming to Paramount+

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Letters: Secret and Broken Family Courts Betrayed Me and My Child | Family law https://star-warz.net/letters-secret-and-broken-family-courts-betrayed-me-and-my-child-family-law/ Sun, 19 Jun 2022 05:00:00 +0000 https://star-warz.net/letters-secret-and-broken-family-courts-betrayed-me-and-my-child-family-law/ It is so gratifying that the Observer and others shine a light on the disaster that is the family court system (“Families Shattered by Unregulated Court Experts”, News, and “How Children’s Lives Can Be Shattered by Family Court Experts”. Unregulated Family”, Special Report). I totally agree and confirm the comments expressed in both articles. “Parental […]]]>

It is so gratifying that the Observer and others shine a light on the disaster that is the family court system (“Families Shattered by Unregulated Court Experts”, News, and “How Children’s Lives Can Be Shattered by Family Court Experts”. Unregulated Family”, Special Report). I totally agree and confirm the comments expressed in both articles. “Parental alienation” is unscientific but is used by abusive partners to discredit the protective parent. It is approved by so-called experts who make money at the expense of the child.

Unfortunately, it is practically impossible to refute such a negative, especially since in my case no “survey” exercise took place. Unlike criminal courts, appearing guilty until proven guilty is the overriding premise. Also in my case, the “expert” had no experience or expertise in my particular case or that of my child, which left us discriminated against.

What my child wanted and expressed clearly and repeatedly was ignored and exceeded. I don’t see any justice in the system, but there is no mechanism to fight it because everything happens behind closed doors. This is compounded if you are in any way disadvantaged.

Protective children and parents are left behind by a broken secret system that needs to change. It must be transparent, based on facts, and not on conjecture or pseudo-science supported by “experts” making money on it, often at the expense of the most vulnerable. In the name of justice, the secrecy of these courts must end.
Name and address provided

Darwin is no mere amateur

“Sometimes dabbling has led to dramatic breakthroughs: Charles Darwin is a famous example.” I see where Martha Gill is coming from (“No talent required in the lucrative new era of the amateur gentleman”, Commentary), in that Darwin had a degree in theology, but biology was not included in the course of natural sciences from Cambridge until 1851 and Darwin graduated 20 years earlier.

Getting a “professional” qualification in biology, anywhere in the world, was nearly impossible in those days. In short, he was about as professional as anyone could have been in the 19th century.
John Horfall
Caterham, Surrey

Unreversible Brexit

William Keegan delivers an excellent analysis of the impact of Brexit on the British economy (“Brexit has reached the gold standard of self-harm”, Business). However, his conclusion that Brexit is reversible is currently not true. To qualify as a member of the EU, any candidate government must prove that it respects international law. This would automatically exclude the UK.
Philippe Bushill-Matthews
Spa in Leamington, Warwickshire

Is that a bomb in your kilt?

In her fascinating article on the launch of the Stuart Christie Memorial Archive (“Anarchist, Publisher, Would-be Assassin: Recording the Legacy of Stuart Christie”, News), Vanessa Thorpe described Christie’s infamous mission, clad in a kilt, to deliver plastic explosives to Madrid in connection with the failed assassination attempt on General Franco in 1964.

In his very entertaining memoirs, Grandma made me an anarchistChristie explained that he wore the kilt because it was a good hiding place for explosives.

This wheezing made him something of a local hero in the west of Scotland, where I was living at the time, as it seemed to Glasgow residents a “purely deid gallus” thing to do. Christie added that her choice of clothes, coupled with her long hair, led to reports in the foreign press that the person who tried to blast Franco was a Scottish transvestite.
Mike Pender
Cardiff

Social housing, the way forward

Sonia Sodha (“The ugly truth behind our rigged housing system – politicians live in fear of landlords”, Commentary) is quite right to state that “the ugly truth at the heart of the housing crisis is that politicians don’t ‘have no incentive to pursue policies that would truly make housing more affordable.’ created this crisis. Adding fuel to a dysfunctional system only makes things worse.

If politicians are serious about providing adequate and affordable housing, they must promote non-market, community-based forms of tenure, such as community land trusts, co-housing and other forms of social housing that could be funded by progressive taxes on properties held for speculative or investment purposes. Which politicians are willing and able to advocate for this?
Geoffrey Payne
London W5

Picasso the executioner

It’s surreal for Dalya Alberge (“Always thought Picasso painted like a child? Well, he wanted to”, News) to write that a child was “born from [Pablo Picasso’s] passionate love for Marie-Thérèse Walter, whom he met in 1927 when she was only 17 and he was 28 years her senior”.

Walter’s pregnancy in 1935 was the occasion for Picasso both to separate (over the years) from his first wife, Olga Khokhlova, whom he never divorced, and to recover his next famous mistress, Dora Maar, during Walter’s pregnancy. Françoise Gilot, still alive at 100 and who succeeded Maar, writes that he had “a Bluebeard complex which made him want to cut off the heads of all the women he had collected in his little private museum.

“But he didn’t cut off heads entirely. He preferred that life go on and that all these women who had shared his life at one time or another still utter little cries and little cries of joy or pain and make a few gestures like disarticulated dolls, just to prove that there was life left in them, that she was hanging by a thread and he was holding the other end of the thread.
Benjamin Letzler
Modling, Austria

Who are you calling classy?

I’m sorry to spoil Melvyn Bragg’s little anecdote about him and Dennis Potter being two of only three true working class members in Oxford when they were there (“This much I know”, Magazine).

I was a student at Ruskin College at the time, and while not everyone there was working class, most were, especially the large contingent of ex-miners.
Dr David Mervin
Arnside, Cumbria

A question of law

Chris Patten tells Tim Adams about his attempts to explain the concept of rule of law to the government in Beijing when he was governor of Hong Kong (“Reflections on the Death of Democracy”, The New Review). Do members of the current British government understand the concept better?

When the late Tom Bingham’s book The rule of law was published in 2010, one reviewer wrote that Bingham explained basic ideas of the rule of law simply and clearly, “as to a child or a minister”.

It has never been more necessary for someone to take cabinet ministers aside and carefully explain what the rule of law means and why it is so important nationally and internationally.
John Filby
Ashover, Derbyshire

There was a crooked man

Jonathan Bouquet refers to the simile uttered by Gideon from Gideon’s Path: “As twisted as a moron’s cane” (Commentary). I prefer the following comparison from Ray White’s book swallow dogwhere a young Missouri plow boy looks back at the two dozen furrows he has just plowed, “each as crooked as a jackleg lawyer”.
John Richards
Bath

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OVPR Announces SPARK Technology Commercialization Fund Recipients for 2022-2023 https://star-warz.net/ovpr-announces-spark-technology-commercialization-fund-recipients-for-2022-2023/ Wed, 15 Jun 2022 20:22:24 +0000 https://star-warz.net/ovpr-announces-spark-technology-commercialization-fund-recipients-for-2022-2023/ The Office of the Vice President, Research (OVPR) is pleased to announce the recipients of the SPARK Technology Commercialization Fund Program 2022-23. Five grantees have been selected for internal funding under the program. They include researchers from UConn and UConn Health. SPARK supports innovative proof-of-concept studies aimed at translating research findings into products, processes, and […]]]>

The Office of the Vice President, Research (OVPR) is pleased to announce the recipients of the SPARK Technology Commercialization Fund Program 2022-23.

Five grantees have been selected for internal funding under the program. They include researchers from UConn and UConn Health.

SPARK supports innovative proof-of-concept studies aimed at translating research findings into products, processes, and other commercial applications. The main goal of the program is to advance the inventions of elementary school teachers to the market, where they can have a positive impact on UConn, society, and Connecticut’s economy.

The 2022-23 winners competed for funding through a highly selective process. Congratulations to the following people:

Laijun LaiUConn, Department of Allied Health Sciences
Targeting TAPBPL in tumor immunotherapy

raman BahalUConn, Department of Pharmaceutical Sciences
Targeted liver and kidney delivery of next-generation miRNA inhibitors using carbohydrate-based conjugates

Eugene PinkhassikUConn, Department of Chemistry
Integrating palladium-catalyzed reactions into continuous manufacturing

Ali TamayolUConn Health, Department of Biomedical Engineering
Design of a Portable One-Step Foaming and Printing Device for the Treatment of Soft Tissue Injuries

Luyi SunUConn, Department of Chemical and Biomolecular Engineering
High performance nanocoatings for packaging applications

For more information about SPARK, visit the program’s website.
Follow UConn Research on Twitter & LinkedIn.

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China investment restrictions gain momentum in talks with US lawmaker https://star-warz.net/china-investment-restrictions-gain-momentum-in-talks-with-us-lawmaker/ Tue, 14 Jun 2022 03:11:59 +0000 https://star-warz.net/china-investment-restrictions-gain-momentum-in-talks-with-us-lawmaker/ The provision is part of sweeping legislation aimed at boosting US competitiveness with China and also granting $52 billion to chipmakers to expand operations in the US. “The refined proposal released today has bipartisan and bicameral support and addresses industry concerns, including the scope of forward-looking activities, industries covered, and avoidance of duplicate authorities,” said […]]]>

The provision is part of sweeping legislation aimed at boosting US competitiveness with China and also granting $52 billion to chipmakers to expand operations in the US.

“The refined proposal released today has bipartisan and bicameral support and addresses industry concerns, including the scope of forward-looking activities, industries covered, and avoidance of duplicate authorities,” said U.S. Senators Bob Casey and John Cornyn, and Representatives Rosa DeLauro, Bill Pascrell. , Jr, Michael McCaul, Brian Fitzpatrick and Victoria Spartz, in a statement.

The initial “outbound investment” proposal had faced opposition over fears it would reduce business investment overseas, leading some chipmakers to oppose its inclusion in the chip bill drafted by Senate and House lawmakers.

Democratic Senator Mark Warner told Reuters on Monday that “time is running out” on the broader chip bill and said there was “a lot of talk” about pivoting to a bill that won’t happen. would focus only on subsidizing factories to manufacture chips, which could depress trade. provisions and other measures to help the United States compete with China in science, business and technology.

The outbound investment measure was originally proposed as a standalone bill by Cornyn and Casey, but was later added to the House version of a massive bill that includes subsidies to chipmakers and targets counter the rise of China.

The bill, which would capture less investment than the original version, drew opposition from critics who said it would hurt American competitiveness. The U.S.-China Business Council said of the new draft, “If such government controls were implemented on a unilateral basis, it would only undermine the flexibility and resilience of American businesses.”

The draft says a new investment committee would engage with allies to coordinate and share information.

The legislation aims to give the U.S. government greater visibility into U.S. investments. It will be mandatory to notify the government of investments that may fall under the new regulations, and the United States can use existing authorities to stop investments or mitigate risk. If no action is taken, the investment can go ahead.

The concept behind the measure is supported within the Biden administration. US President Joe Biden’s national security adviser, Jake Sullivan, said in July that the government was working on new investment screening and considering overseas investments as it sought to better position the United States to competition in the field of technology.

A study by Rhodium indicated that 43% of U.S. foreign direct investment transactions in China over the past two decades could have been screened into the broad categories defined by the original proposal.

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Wallace Shawn blesses season 3 struggling with a weight problem https://star-warz.net/wallace-shawn-blesses-season-3-struggling-with-a-weight-problem/ Sun, 12 Jun 2022 14:00:00 +0000 https://star-warz.net/wallace-shawn-blesses-season-3-struggling-with-a-weight-problem/ Ben Shakir is the most academic on this case, and Aasif Mandvi brings real seriousness to the argument. Ben sees the whole experience as a crutch for the church, and the commitment the actor brings to it is palpable. His mindset is diametrically opposed to this concept in the most analytically grounded way. Ben’s disdain […]]]>

Ben Shakir is the most academic on this case, and Aasif Mandvi brings real seriousness to the argument. Ben sees the whole experience as a crutch for the church, and the commitment the actor brings to it is palpable. His mindset is diametrically opposed to this concept in the most analytically grounded way. Ben’s disdain for fringe science is well countered by David’s righteous curiosity, something he has in abundance. The priest doesn’t really care about theosophical questions, he really wants to know if science can find a soul. The bad news is that the research team needs a living subject. The good news is that he is played by Wallace Shawn.

Father Frank has the biggest arc of any character invited to appear on Bad, so far. Not only does he go to heaven and back, but he returns as a new man, open to change and to the experiences he had to suppress from his entire earthly existence. During his final confession, it seems the dying priest is still searching for clues of God’s love. There is a search visible in Shawn’s eyes as Father Frank considers David’s words before accepting this as a human failure. The real experience is captured with the cold clinical distance of the researchers, amid deep emotional expressions between Father Frank and Monsignor Matthew Korecki (Boris McGiver). The starkest contradiction comes when the team applauds the death of the priest. Later, Shawn brings joy to the proceedings. “I’m a medical mystery,” he laughs. Shawn’s take is so wonderfully understated yet carries the weight of a new soul.

“Responsibility is a cross that we all have to bear,” Leland said, shortly before he was caught by an accountant. He has been instructed by the Cardinal to look after David, who can barely conceal the disgust he feels at being in the same room. When Kristen slaps the pompous overseer with a restraining order, in one of the show’s most deliciously served entries, the newly ordained priest administers the last few laughs. The scene is remarkably versatile, mixing a lukewarm undercurrent of sexual energy with the wave of cold revenge, swinging forever on subtle slapstick, until Ben knocks it down with a Beethoven fifth.

Kristen’s family life continues to be a drag, especially her husband Andy (Patrick Brammall), but it’s all perhaps part of Kristen’s mother Sheryl’s (Christine Lahti) most insidious plan: to entice the public to push him out of the house as much as possible. she does. He’s good for one thing, and it’s not plumbing. Who flushes a shrunken head down the toilet? It almost sounds like he’s intentionally trying to kick himself out of the show.

The all-too-short intro scene between Kristen and Sister Andrea (Andrea Martin) is illuminating and heartwarming. It highlights a mutual respect, but it seems that it should carry a distrust. Sister Andrea is more than a true believer. She’s a visionary with the foresight to spill hot tea on peripheral troubles. Kristen is a mass of contradictions, who has a bad habit of speaking the language of love in forked tongues. The conclusion, of course, heats up the mystery of the group dynamics. The audience can see it very clearly in David’s seemingly lying eyes: he has no idea what, if anything, is going on with Kristen. It’s still exciting to watch.

The special effects are uniformly well done in the episode, from the surges in the research team’s observation lab to the icky residue that the pickled head of satanic royalty leaves in the toilet. The sterile environment is assaulted by energy until it becomes an open wound. Family bathroom becomes a bloody sewer at the Overlook Hotel the brilliant. Kristen’s forked tongue looks like it was done by a professional.

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3 new disease-fighting technologies you should know about before BIO 2022 https://star-warz.net/3-new-disease-fighting-technologies-you-should-know-about-before-bio-2022/ Thu, 09 Jun 2022 21:03:19 +0000 https://star-warz.net/3-new-disease-fighting-technologies-you-should-know-about-before-bio-2022/ Published on Thursday, June 9, 2022 Researchers from the University of Chicago and representatives from the Polsky Center for Entrepreneurship and Innovation will participate in the BIO International Convention. (Image: iStock.com/Design Cells) Researchers at the University of Chicago have developed methods to increase the clinical effectiveness of immunotherapies, provide long-lasting immune tolerance for autoimmune or […]]]>

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Researchers from the University of Chicago and representatives from the Polsky Center for Entrepreneurship and Innovation will participate in the BIO International Convention. (Image: iStock.com/Design Cells)

Researchers at the University of Chicago have developed methods to increase the clinical effectiveness of immunotherapies, provide long-lasting immune tolerance for autoimmune or transplant therapies, and treat breast and ovarian cancer with small molecules.

// FOXP3-stapled peptides to deactivate regulatory T cells

Although there have been advances in improving the immune response to various new therapies, the presence of regulatory T cells (Tregs) remains a significant challenge to clinical efficacy.

Tregs are a specialized subpopulation of T cells that act to suppress the immune response, playing a critical role in the prevention of autoimmunity. They prevent T cells from mounting an immune response against antigens in the body, including those that would normally target cancer cells.

For this reason, Treg activity can significantly limit the effectiveness of immunotherapies, making a method of reducing Treg activity highly desirable for the overall advancement of the field.

By targeting the transcription factor FOXP3, which is selectively expressed in Tregs and required for Treg function, researchers have now synthesized stapled alpha-helical peptides that block FOXP3 signaling, thereby inhibiting Treg function.

In early proof-of-concept studies, alpha-helical stapled peptides bound to recombinant FOXP3 with nanomolar affinity and reduced expression of FOXP3-regulated genes.

Advantages:

  • Lower potential for drug resistance than therapeutic antibodies
  • Fewer off-target effects than small molecules

Apps:

  • Immuno-oncology
  • Combination therapy: (chemotherapy, radiotherapy, immunotherapy)

This research is led by University of Chicago researcher James LaBelle, associate professor of pediatrics. The research group is excited about the recently completed in vivo mouse model studies for the FoxP3 project. A manuscript is pending.

The primary focus of his lab is to dissect and pharmacologically target intracellular proteins to induce cancer cell death and manipulate the immune response. Much of this work is focused on using portions of the actual proteins, or peptides, as drugs and biological tools to uncover specific molecular pathways in diseased and normal cells.

// Tolerization of agonist/immunomodulator-loaded liposomes for long-lasting immune tolerance

According to the National Institutes of Allergy and Infectious Diseases, more than 80 illnesses arise when the immune system attacks the body’s own organs, tissues, and cells.

The main cause of many of these autoimmune diseases is a failure of central immune tolerance: the body becomes unable to eliminate T or B cells, which produce the antibodies used to attack bacteria, viruses and toxins.

This failure is usually caused by self-antigen-specific Treg cells, and although the reasons for this failure vary, restoring an appropriate self-antigen-specific response would provide a very effective long-term therapy for a range of autoimmune diseases.

By targeting these cells, researchers have developed a method that generates antigen-specific immune tolerance for autoimmune or transplantation therapy by inducing dendritic cells with three immunosuppressive drugs.

Used in combination with toll-like receptor (TLR) agonists – which increase T-cell responses and down-regulate the suppressive effects of Tregs – a potent tolerogenic dendritic cell (tolDC) phenotype is generated, subsequently creating antigen-specific Treg cells.

Today, the most effective therapies are age-old drugs that have significant side effects and do not address the root cause of the disease. And the occurrence of these diseases is increasing in the United States, according to a study published in 2020 by the National Institutes of Health.

Advantages:

  • Reliable generation of antigen-specific Tregs with minimal non-specific immune suppression
  • Long-lasting immune tolerance
  • Easy manufacture and storage

Apps:

  • Autoimmune diseases
  • Transplant medicine

This work is led by Aaron Esser-Kahn, associate professor of molecular engineering at the University’s Pritzker School of Molecular Engineering, whose research interests lie at the intersection of biology, chemistry, and science of molecules. materials. His main area of ​​research focuses on immunoengineering and improving immune responses in vaccination.

// New small molecules for the treatment of breast and ovarian cancer

The development of breast cancer is driven by the pro-oncogenic cellular activities of the estrogen receptor alpha (ERα), which is overexpressed in about 70% of breast cancers.

For this reason, the use of ERα-targeting therapies is a leading strategy to prevent the progression or spread of breast cancer – the most common cancer among women in the United States.

While acquired resistance to these therapies is a major source of breast cancer mortality, more potent antiestrogens have, in preclinical models, demonstrated the ability to overcome these issues. Specifically, selective estrogen receptor (ER) degraders, or downregulators, which antagonize the actions of ERα and induce its degradation, have demonstrated substantial antitumor efficacy.

A promising treatment for breast cancer, in addition to ovarian cancer and osteoporosis, University researchers have developed a set of novel small molecules with enhanced therapeutic activities.

Advantages:

  • Molecules take on a new orientation in proteins and have a unique scaffold compared to other anti-estrogens
  • Unique pharmacological profiles
  • Potential for significant enhancement of tissue-specific activities that are important contributors to side effects

Apps:

  • Breast cancer
  • Ovarian cancer
  • Osteoporosis

// Contact Michael HintonManager of Market Intelligence, who will be at BIO 2022 and can provide more details on these and other technologies, discuss the licensing process and connect you with inventors.


Article by Melissa Fassbender, senior associate director of external relations and scientific communications at the Polsky Center. Melissa is a former journalist and has served as an editor in various global publications in the field of drug development, clinical trials and design engineering. Contact Melissa via email or Twitter at @melfass.

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World’s first measurement of magnetic field-dependent stimulated emission https://star-warz.net/worlds-first-measurement-of-magnetic-field-dependent-stimulated-emission/ Tue, 07 Jun 2022 14:11:09 +0000 https://star-warz.net/worlds-first-measurement-of-magnetic-field-dependent-stimulated-emission/ Demonstrator of a laser threshold magnetometer. The perspective shows the cavity where the scientists measured the amplification and the magnetic field-dependent stimulated emission. Credit: Fraunhofer-Institut für Angewandte Festkörperphysik IAF In medical care, the magnetic fields of heart and brain activity are measured to detect disease at an early stage. To measure even the smallest magnetic […]]]>

Demonstrator of a laser threshold magnetometer. The perspective shows the cavity where the scientists measured the amplification and the magnetic field-dependent stimulated emission. Credit: Fraunhofer-Institut für Angewandte Festkörperphysik IAF

In medical care, the magnetic fields of heart and brain activity are measured to detect disease at an early stage. To measure even the smallest magnetic fields, Fraunhofer IAF researchers are working on a new approach: diamond-based laser threshold magnetometry. The idea is to use diamond with a high density of nitrogen vacancy centers in a laser system. Today, the researchers succeeded in reaching an important milestone: they were able to demonstrate the world’s first measurement of magnetic field-dependent stimulated emission and even set a new contrast record. The results were published in the journal Scientists progress.

In medical diagnostics, sensitive sensors are needed to measure, for example, the weak magnetic fields of heart and brain activity (MCG, MEG) of the human body and to create images of the body via magnetic resonance imaging (MRI). ), which allows the detection of diseases at an early stage. However, only a few highly sensitive magnetic field sensors achieve the necessary accuracy and each of them presents major technical hurdles for clinical application.

Already established SQUID sensors require complex cryogenic cooling of around -270°C. Vapor cell magnetometers (OPM) are another option. Although these achieve the highest sensitivities even without cryogenic cooling, they have the disadvantage of requiring absolute shielding from all background fields, including the earth’s magnetic field, and thus impose massive structural demands on parts and to buildings. For this reason, the most inaccurate electrical measurements (ECG, EEG) continue to be common in daily clinical practice.

At the Fraunhofer Institute for Applied Solid State Physics IAF in Freiburg, a project team is already researching a more suitable alternative: “Our goal is to develop an extremely sensitive magnetic field sensor that operates at room temperature as well as in the presence of background fields and is therefore useful for clinical implementations,” says Dr. Jan Jeske, project manager at Fraunhofer IAF.

Measure the smallest magnetic fields with diamond and laser

In the project “NV-doped CVD Diamond for Ultra-Sensitive Laser Threshold Magnetometry” (abbreviation “DiLaMag”), Jeske and his team are researching a globally unique approach to highly sensitive quantum magnetic field sensors. For the first time, they use diamond in a laser system, allowing much more precise magnetic field measurements.

For the project, the diamond is doped with a high density of nitrogen vacancy centers (NV centers). “Due to its material properties, diamond with a high density of NV centers can significantly improve measurement accuracy when used as a laser medium,” says Jeske. NV centers in diamond are atomic systems consisting of a nitrogen atom and a carbon defect. They absorb green light and emit red light. Since the fluorescence of these atomically small NV centers depends on the strength of an external magnetic field, they can be used to measure magnetic fields with high local resolution and good sensitivity.

World's first measurement of magnetic field-dependent stimulated emission

The diamond sample has a high NV concentration after irradiation, which is responsible for the pink color. Credit: Fraunhofer-Institut für Angewandte Festkörperphysik IAF

First experimental demonstration of laser threshold magnetometry

After several years of research effort, Jeske’s team has reached an important milestone: they have demonstrated the world’s first measurement of magnetic field-dependent stimulated emission. In the process, the researchers made an interesting discovery: “We observed a very relevant and previously unknown physical process in NV diamond: the absorption of red light induced by green laser irradiation,” reports Jeske.

By using NV diamond as the laser medium, they not only achieved a 64% amplification of signal power by stimulated emission. The project team was even able to set a world record: the magnetic field-dependent emission shows a contrast of 33% and maximum output power in the mW regime. This is a new contrast record in magnetometry with NV sets.

Stimulated emission is responsible for this. “We were able to show that this record would not have been possible with spontaneous emission. Thus, we have experimentally demonstrated for the first time the theoretical principle of laser threshold magnetometry”, emphasizes Jeske.

These results also show the advantages of diamond-based laser threshold magnetometry over conventional methods and prove that it is possible to measure the smallest magnetic fields.

Great progress in the production of NV diamonds

The concept of laser threshold magnetometry only works if the diamond has a very high density of NV centers while maintaining good optical properties. For this reason, the project team did extensive material work to optimize the diamond accordingly. This work includes, on the one hand, diamond production by CVD (chemical vapor deposition) and, on the other hand, post-processing by electron irradiation and heat treatment for an increase in NV density.

During diamond growth by CVD, which allows a very precise and controlled integration of the NV centers, the researchers have already been able to achieve a strong nitrogen doping. Using electron irradiation, they then determined an optimal fluence for nitrogen density, which resulted in a 20- to 70-fold increase in NV density. The absorption spectra allowed them to follow the formation of NV centers live.

During the characterization, they established the correlations between three crucial factors for optimal NV sets and optimized them: high NV density, high conversion of substituted nitrogen using high fluence irradiation and charge stability. high. As a result of these detailed studies, the Fraunhofer IAF team succeeded for the first time in producing CVD diamond with a high density of NV centers and good quality, thus creating the prerequisite for the development of laser threshold magnetometry. diamond-based for measuring extremely small magnetic fields.


Toward Superior Nanoscale Detection and Imaging with Optimized Diamond Probes


More information:
Felix A. Hahl et al, Magnetic field-dependent stimulated emission from nitrogen vacancy centers in diamond, Scientists progress (2022). DOI: 10.1126/sciadv.abn7192

T Luo et al, Creation of Nitrogen Void Centers in Chemical Vapor Deposition Diamond for Sensing Applications, New Journal of Physics (2022). DOI: 10.1088/1367-2630/ac58b6

Julia Langer et al, Manipulation of the In Situ Nitrogen-Vacancy Doping Efficiency in CVD-Grown Diamond, solid physical state (a) (2022). DOI: 10.1002/pssa.202100756

Provided by Fraunhofer-Institut für Angewandte Festkörperphysik IAF

Quote: World’s first measurement of magnetic field-dependent stimulated emission (2022, June 7) retrieved June 7, 2022 from https://phys.org/news/2022-06-world-magnetic-field-dependent-emission.html

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