Science concept – Star Warz http://star-warz.net/ Sat, 15 Jan 2022 06:24:22 +0000 en-US hourly 1 https://wordpress.org/?v=5.8 https://star-warz.net/wp-content/uploads/2021/06/icon-2021-06-23T234539.702-150x150.png Science concept – Star Warz http://star-warz.net/ 32 32 The most watchable sci-fi shows of all time https://star-warz.net/the-most-watchable-sci-fi-shows-of-all-time/ Sat, 15 Jan 2022 03:44:00 +0000 https://star-warz.net/the-most-watchable-sci-fi-shows-of-all-time/ A historical sci-fi drama, “The X-Files” went from quirky procedural to cultural touchstone, and made David Duchovny and Gillian Anderson true superstars. A twist on the buddy cop format, Duchovny played veteran FBI agent Fox Mulder, a conspiracy-obsessed believer in all things extraterrestrial and supernatural, while Anderson was Agent Dana Scully, the skeptical rookie at […]]]>

A historical sci-fi drama, “The X-Files” went from quirky procedural to cultural touchstone, and made David Duchovny and Gillian Anderson true superstars. A twist on the buddy cop format, Duchovny played veteran FBI agent Fox Mulder, a conspiracy-obsessed believer in all things extraterrestrial and supernatural, while Anderson was Agent Dana Scully, the skeptical rookie at the fresh face joined him in the bowels of the agency. Together, the mismatched pair have been tasked with investigating the so-called X-Files: cases involving the possible paranormal or otherwise extraordinary. Featuring alien abductions, mutant experiments, werewolves, and vampires, the series was a crowd-pleasing mix of sci-fi, horror, and crime drama. Although the series had its darkest moments, it rarely took itself too seriously, which added to its considerable charm.

Ran for nine initial seasons between 1993 and 2002, it was revived for two more in 2016, and even had two theatrical movies, one of which was released between its fifth and sixth seasons. The series had a few ongoing subplots, but was mostly episodic in nature, with a new case and threat almost every week. A delight to watch again for more than engaging stories, it’s also fun to look back and see all the future stars who passed through its doors, including Bryan Cranston (“Breaking Bad”), Ryan Reynolds (“Deadpool” ), Lucy Liu (“Elementary”), and Michael Emerson (“Lost”).

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Shanghai ZhenGe Biotech raises $ 100 million in Round C led by Goldman Sachs Asset Management and Sofina https://star-warz.net/shanghai-zhenge-biotech-raises-100-million-in-round-c-led-by-goldman-sachs-asset-management-and-sofina/ Tue, 11 Jan 2022 14:15:00 +0000 https://star-warz.net/shanghai-zhenge-biotech-raises-100-million-in-round-c-led-by-goldman-sachs-asset-management-and-sofina/ SHANGHAI, January 11, 2022 / PRNewswire / – Shanghai ZhenGe Biotech Co., Ltd. (“ZhenGe Biotech” or “the Company”) announced the finalization of the financing of round C of the $ 100 million, led by Goldman Sachs Asset Management and Sofina. Novo Holdings A / S, Qiming Venture Capital, IDG Capital, LYFE Capital, Junxin Capital and […]]]>

SHANGHAI, January 11, 2022 / PRNewswire / – Shanghai ZhenGe Biotech Co., Ltd. (“ZhenGe Biotech” or “the Company”) announced the finalization of the financing of round C of the $ 100 million, led by Goldman Sachs Asset Management and Sofina. Novo Holdings A / S, Qiming Venture Capital, IDG Capital, LYFE Capital, Junxin Capital and Cowin Capital have also invested.

the product Round C will be used to strengthen ZhenGe Biotech’s global R&D capabilities and expand its Good Manufacturing Practices (“GMP”) manufacturing capacity to better meet domestic and international customer demand. To date, the Company has raised a total of US $ 225 million.

ZhenGe Biotech provides one-stop contract development and manufacturing organization (CDMO) services and offers end-to-end solutions to help customers discover, develop and manufacture biologics from concept to commercialization. To date, the company has served over 100 biopharmaceutical and biotechnology clients and completed over 150 projects, ranging from cell line development projects to new investigational drug (IND) applications and large clinical phase production contracts. Over the years, ZhenGe Biotech has developed deep expertise in monoclonal and bispecific antibodies, antibody-drug conjugates (ADCs), fusion proteins and vaccines.

ZhenGe Biotech integrates advanced cell culture platform, metabolite analysis platform, recombinant protein analysis platform, and customized media development and production platform for customers to improve yield and quality of securities. Additionally, ZhenGe Biotech provides advanced analytical services including Analytical Ultracentrifugation (AUC) to assist customers with overseas drug approval requests.

In addition to R&D centers through Shanghai and Maryland, United States, ZhenGe Biotech owns 10,000 GMP pilot production center in Lingang Special Zone of China (Shanghai) Pilot Free Trade Zone (FTZ), a medium GMP production line with an annual output of 200 tonnes of dry powder, and a commercial manufacturing base with three 2,000L and three 5,000L bioreactors, currently under construction.

ZhenGe Biotech also focuses on environmental, social and governance (ESG) responsibilities as part of its strategy and strives to create a positive impact by adhering to high environmental, health and safety standards while by adopting next-generation manufacturing technologies and cleaner energy sources.

Mr. Jianxin Chen, Chairman and CEO of ZhenGe Biotech said, “We are delighted that global investors like Goldman Sachs Asset Management, Sofina and Novo Holdings are leading the current funding round, and we thank them for their support. Tower C product will be used to strengthen our R&D and build multiple 15,000L production lines, which will enable ZhenGe Biotech to provide cost-effective and high-quality solutions to meet growing demand from existing and new customers. “

“Against the backdrop of a large and rapidly growing global biologics market, we see continued innovation in drug development driven by regulatory policy and capital formation. We expect the rate of outsourcing of macromolecular drug development to increase as innovative players begin to face talent constraints. We are excited about the solutions that ZhenGe can offer to its customers, as well as its extensive know-how in upstream and downstream processes to help arrive at viable cell lines, ”said Kevin Xu, Managing Director of Goldman Sachs Asset Management, which focuses on the company’s investment efforts in healthcare and life sciences in China. Mr. Xu is now a member of the board of directors of the company.

Sofa head of China Xiao-Tian Law and Chief Investment Officer, Lim Yizhen, said, “We are delighted to support ZhenGe which has been on a trajectory of rapid growth given its strong combination of in-depth technical expertise and commitment to providing customers with the advanced manufacturing and process excellence in the development and production of affordable products. and innovative therapies. We are confident that ZhenGe will continue to be a trusted partner of choice for new and existing customers and we are delighted to embark on a long term partnership with ZhenGe. “

Dr. Amit Kakar, Senior Partner and Head of Novo Holdings Asia said, “ZhenGe Biotech is one of the fastest growing biologics CDMOs addressing a large unmet need through its high quality end-to-end services led by a leading team in the sector. Novo Holdings is very happy to partner with them in the implementation of their national and international growth strategy.

About Goldman Sachs Asset Management Growth Equity

Bringing together traditional and alternative investments, Goldman Sachs Asset Management offers its clients around the world a dedicated partnership focused on long-term performance. As the primary investment area within Goldman Sachs (NYSE: GS), we provide investment and advisory services to the world’s leading institutions, financial advisors and individuals, leveraging our deeply connected global network and bespoke expert information, in all regions and markets, overseeing $ 2.37 trillion in assets under surveillance worldwide September 30, 2021. Driven by a passion for the performance of our clients, we seek to build long-term relationships based on conviction, lasting results and shared success over time. follow us on LinkedIn.

About Sofina

Sofina is a family-owned investment company listed on Euronext Brussels, managing its own assets which represent approx. 10 billion euros. Sofina aspires to be the privileged partner of entrepreneurs and families who run growing businesses by supporting them with patient capital and supportive advice. As part of its Sofina Growth investment style, it takes minority stakes, generally in the range of 15 to 50 million euros. A common vision and a strong alignment of interests with its partners are essential in the deployment of the strategy. For more information, visit www.sofinagroup.com.

About Novo Holdings A / S

Novo Holdings A / S is a private limited liability company wholly owned by the Novo Nordisk Foundation. It is the holding company of the Novo group, comprising Novo Nordisk A / S and Novozymes A / S, and is responsible for the management of the assets of the Novo Nordisk Foundation.

Novo Holdings is recognized as a leading international investor in life sciences with a focus on long-term value creation. As an investor in the life sciences, Novo Holdings provides seed and venture capital to early stage companies and takes significant stakes in growing and established companies. Novo Holdings also manages a large portfolio of diversified financial assets. More information: www.novoholdings.dk.

About ZhenGe Biotech

Shanghai ZhenGe Biotech was founded in 2017. ZhenGe Biotech’s main business is CDMO service of macromolecular biological drugs, development and production of mammalian cell culture media, etc. Specifically, its services include: macromolecule developability analysis, cell line development, process development and optimization, pilot production, clinical sample production and commercial CMO services, characterization research and process validation, drug analysis services, development of cell culture media formulations and commercial production, etc.

SOURCE Shanghai ZhenGe Biotech Co., Ltd.

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Six innovation centers to promote medicinal plants https://star-warz.net/six-innovation-centers-to-promote-medicinal-plants/ Sun, 09 Jan 2022 14:19:47 +0000 https://star-warz.net/six-innovation-centers-to-promote-medicinal-plants/ TEHRAN – The Vice Presidency for Science and Technology has established six innovation centers to develop the supply chain for medicinal plants in the country. The innovation centers were established in the cities of Tehran, Kermanshah, Ardebil, Hamedan, Yasouj and Gonabad, with the aim of paving the way for industries for easier access to ideas […]]]>

TEHRAN – The Vice Presidency for Science and Technology has established six innovation centers to develop the supply chain for medicinal plants in the country.

The innovation centers were established in the cities of Tehran, Kermanshah, Ardebil, Hamedan, Yasouj and Gonabad, with the aim of paving the way for industries for easier access to ideas and products in the field of medicinal plants. , IRNA reported on Sunday.

Fifteen other requests [for creating innovation centers] are also awaiting approval, the report adds.

The Vice Presidency for Science and Technology has taken technological steps to make this ancient industry in the country thrive. These measures include the development of a promotional package to develop the production and use of these products.

“Using the capacity of national media and supporting national and international exhibitions and festivals in the field of medicinal plants” and “Using the capacity of education to promote the importance of medicinal plants in primary and secondary education” are included. among other actions.

In addition, “promoting culture and reforming the attitude of society towards traditional medicine and promoting a healthy lifestyle” and “establishing a database of available traditional medicines” and “the establishment of a system for registering traditional and herbal medicines and providing pharmaceutical information” were also implemented.

Iranian traditional medicine is one of the oldest forms of traditional medicine. It is based on the concept of the four senses of humor: phlegm (Balgham), blood (Dam), yellow bile (Safra ‘) and black bile (Sauda’). The concept of the four senses of humor is based on the teachings of Rhazes and Avicenna in an elaborate medical system.

Iranian traditional medicine strongly focuses on prioritizing health maintenance and disease prevention over treatment.

Iran ranked fourth for publishing articles in the field of traditional medicine and herbal medicines around the world, ISNA said citing Nafiseh Hosseini, an official at the health ministry.

Iran also won the fifth place for the production of traditional medicine and herbal medicine knowledge in the world in 2020, but this year the country has improved and ranked fourth after India, China and the United States, added Hosseini.

Progress has been made over the past 10 years, she noted.

The Vice Presidency for Science and Technology has so far registered 120 national standards for herbal and traditional medicine to support the industry.

So far, around 30,000 plant species have been identified worldwide, with Iran’s share of around 8,000 species being greater than that of Europe as a whole.

Currently, about 2300 species of medicinal plants have been identified in the country, accounting for one third of the drugs used in human societies, the global trade share of these products is about 124 billion dollars, and Iran’s share. is $ 570 million, or just 0.5 percent of the total.

The per capita consumption of medicinal plants in Iran is about one kilogram of dried plants. In other words, 83,000 tons of medicinal plants worth 1,200 billion rials (about 4.5 million dollars) are consumed in the country, while in Europe this quantity is 900 grams and in United States of 2.5 kilograms.

MG


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Decrease the side effects of anticancer drugs https://star-warz.net/decrease-the-side-effects-of-anticancer-drugs/ Sat, 08 Jan 2022 02:04:53 +0000 https://star-warz.net/decrease-the-side-effects-of-anticancer-drugs/ image: Schematic of cellulose nanocrystals capturing chemotherapeutic drugs with their charged and designed hairy extensions. see Following Credit: Terasaki Institute for Biomedical Innovation (LOS ANGELES) – Millions of people around the world are touched by cancer every year; over 39% of men and women are diagnosed with cancer in their lifetime. Chemotherapy is the most […]]]>

image: Schematic of cellulose nanocrystals capturing chemotherapeutic drugs with their charged and designed hairy extensions.
see Following

Credit: Terasaki Institute for Biomedical Innovation

(LOS ANGELES) – Millions of people around the world are touched by cancer every year; over 39% of men and women are diagnosed with cancer in their lifetime. Chemotherapy is the most commonly used standard cancer treatment, and targeted administration of these drugs to the tumor site increases their effectiveness. However, too much medication can still circulate around the rest of the body and cause multiple side effects, including anemia, chronic infections, hair loss, jaundice, and fever.

A number of proposed methods have been attempted to remove unwanted chemotherapeutic drugs from the blood, particularly the widely used drug doxorubicin (DOX). But these methods resulted in insufficiently low DOX removal levels. Additional strategies that use electrically charged nanoparticles to bind DOX lose their effectiveness with exposure to charged molecules and proteins present in the blood, despite the addition of materials intended to protect the binding ability.

A collaborative team, which included scientists from Pennsylvania State University and the Terasaki Institute for Biomedical Innovation (TIBI), developed a method to address these challenges.

The method, described in Materials today Chemistry, is based on hairy cellulose nanocrystals – nanoparticles developed from the main component of plant cell walls and designed to have immense numbers of polymer chain “hairs” extending at each end. These bristles increase the potential drug uptake capacity of nanocrystals significantly beyond that of conventional nanoparticles and other materials.

To produce the hairy cellulose nanocrystals capable of capturing chemotherapy drugs, the researchers chemically treated the cellulose fibers found in softwood pulp and imparted a negative charge to the hair, making it stable against the charged molecules present in it. the blood. This corrects the problems encountered with conventional nanoparticles, whose charge can be rendered inert or reduced when exposed to blood, limiting the number of positively charged drug molecules to which they can bind in insignificant numbers.

The binding efficiency of nanocrystals was tested in human serum, the protein-rich liquid part of the blood. For every gram of hairy cellulose nanocrystals, more than 6000 milligrams of DOX were effectively removed from the serum. This represents an increase in DOX capture of two to three orders of magnitude compared to other methods currently available.

In addition, the capture of DOX occurred immediately after the addition of the nanocrystals and the nanocrystals had no toxic or harmful effect on red blood cells in whole blood or on cell growth of human umbilical cells.

Such a powerful means of drug uptake in the body can have a big impact on cancer treatment regimens, as doses can be raised to more effective levels without worrying about harmful side effects.

Principal investigator Amir Sheikhi, assistant professor of chemical and biomedical engineering at Penn State, offered an example of such an application. “For some organs, like the liver, chemotherapy can be given locally through catheters. If we could place a device based on the nanocrystals to capture excess drugs exiting the inferior vena cava of the liver, a major blood vessel, clinicians could potentially administer higher doses of chemotherapy to kill cancer faster without fear. damage healthy cells. Once the treatment is complete, the device can be removed.

In addition to removing excess chemotherapy drugs from the body, hairy cellulose nanocrystals could also target other unwanted substances such as toxins and addictive drugs to be eliminated from the body, and experiments have also shown the effectiveness of the drugs. nanocrystals in other separation applications, such as in the recovery of valuable items from electronic waste.

“What started out as a relatively simple concept has grown into a very efficient way of separating materials,” said Ali Khademhosseini, director and CEO of the Terasaki Institute for Biomedical Innovation. “This creates potential for large-scale and impactful biomedical and scientific applications of materials. “

The other authors are Sarah AE Young, Joy Muthami, Mica Pitcher, Petar Antovski, Patricia Wamea, Robert Denis Murphy, Reihaneh Haghniaz, Andrew Schmidt and Samuel Clark.

This work was supported by the National Institutes of Health (1R01EB024403-01).

PRESS CONTACT

Stewart Han, shan@terasaki.org, +1 818-836-4393

Terasaki Institute for Biomedical Innovation

###

The Terasaki Institute for Biomedical Innovation (terasaki.org) is a non-profit research organization who invents and promotes practical solutions that restore or improve the health of individuals. Research at the Terasaki Institute builds on scientific advancements in understanding what makes each person unique, from the macro-scale of human tissues to the micro-scale of genes, to create technological solutions to some of the problems. most urgent medical conditions of our time. We use innovative technological platforms to study human disease at the individual patient level by incorporating advanced computer and tissue engineering methods. The results of these studies are translated by our research teams into tailored diagnostic and therapeutic approaches encompassing custom materials, cells and implants with unique potential and wide applicability to a variety of diseases, disorders and injuries.

The Institute is made possible by an endowment from the late Dr. Paul I Terasaki, a pioneer in the field of organ transplant technology.


Warning: AAAS and EurekAlert! are not responsible for the accuracy of any press releases posted on EurekAlert! by contributing institutions or for the use of any information via the EurekAlert system.


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Fort Worth Stock Show and Rodeo return in 2022 with new attractions, traditional favorites – NBC 5 Dallas-Fort Worth https://star-warz.net/fort-worth-stock-show-and-rodeo-return-in-2022-with-new-attractions-traditional-favorites-nbc-5-dallas-fort-worth/ Thu, 06 Jan 2022 01:40:49 +0000 https://star-warz.net/fort-worth-stock-show-and-rodeo-return-in-2022-with-new-attractions-traditional-favorites-nbc-5-dallas-fort-worth/ Rodeo fans and thousands of Texas 4-H and FFA youths await the start of the 125th Fort Worth Stock Show & Rodeo as it begins its 23-day run on January 14. According to FWSSR officials, the Stock Show sets the tone for the season of professional rodeo and cattle competitions as it offers millions of […]]]>

Rodeo fans and thousands of Texas 4-H and FFA youths await the start of the 125th Fort Worth Stock Show & Rodeo as it begins its 23-day run on January 14.

According to FWSSR officials, the Stock Show sets the tone for the season of professional rodeo and cattle competitions as it offers millions of cattle scholarships and bonuses as well as a purse of over $ 1 million for the ProRodeo tournament.

“We are already feeling the excitement of our fans for The Stock Show,” said FWSSR President and CEO Brad Barnes. “Ticket sales have been very strong with many of our rodeo shows and concerts nearing sold out, and registrations for our cattle and horse competitions were also at high levels. Obviously, the return to the Stock Show is on the calendar for thousands of people. people across the state and across the country. “

Rodeo returns to Dickies Arena where 25 rodeo performances give fans the chance to take in the sights, sounds and excitement of the iconic celebration of the Western way of life in Fort Worth, FWSSR officials said.

Stock Show rodeos include Best of the West Ranch Rodeo (January 14-15), Best of Mexico Celebraciòn (January 16), Cowboys of Color Rodeo (January 17), Bulls’ Night Out Xtreme Bull Riding (January 18) and 19), Texas Champions Challenge Rodeo (January 20) and the FWSSR PRORODEO tournament (January 21 – February 5).

Following the successful debut of its Auditorium concert series in 2020, the Stock Show has expanded the series to feature Grammy and Oscar-winning artists including legendary rock band Kansas, alternative country music group The Old 97’s, the Country music artist Clint Black, comedian Jeff Foxworthy, the Fort Worth Symphony with singer Tony Vincent performing Queen’s Music, and Ryan Bingham.

The FWSSR Texas Invitational Mariachi competition will also be returning to feature the best high school mariachi teams from across the state, FWSSR officials said.

Officials said the Stock Show has also expanded to the Escaramuza women’s exercise team competition to include the thrilling Charro Cala, starring Alejandro Goñi Rojo, one of Mexico’s top horse and Cala trainers. .

Fans of horse racing will also appreciate the return of the popular Mustang Magic competition, as well as the Mustang Showcase training clinics.

Officials say collegiate ranch horse teams from Texas and Arkansas will enter a new competition at the launch of “Bridles and Brains,” a new concept of collegiate ranch horse competition that puts the horses to the test. equestrian and communication skills.

Fans of Stock Show will enjoy the Moo-seum experience which gives access to nearby museums, courtesy of the Central Market.

General admission to the Stock Show will also include access to the National Cowgirl Museum and Hall of Fame, the Fort Worth Museum of Science and History and the Cattle Raisers Museum, officials said.

Among the activities available at these museums will be “Enter the Stock Show,” the most recent joint effort between the Fort Worth Museum of Science and History and the Stock Show. The collaboration combines artifacts, videos and images provided by the Stock Show with technologies used by the Museum of Science and History to offer museum visitors a unique look at history and the contemporary exhibit on the livestock.

According to FWSSR officials, while there is plenty of new stuff in store for 2022, the Stock Show’s traditional entertainment options remain popular.

Breeding and horse shows are central to the identity of the Stock Show, and thousands of animals will be on display this year competing for millions of auction proceeds and bonuses, officials said.

Acres of “rodeo shopping” that includes everything from fashion to farm equipment.

Family entertainment will also be available with options such as the Mattress Firm petting zoo, children’s barnyard, Carnival Midway, Texas Farm Bureau Insurance’s Planet Agriculture, and the milking parlor.

Ticket information can be found here.


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Liquid Death lands $ 75 million more to expand brand – TechCrunch https://star-warz.net/liquid-death-lands-75-million-more-to-expand-brand-techcrunch/ Tue, 04 Jan 2022 01:52:30 +0000 https://star-warz.net/liquid-death-lands-75-million-more-to-expand-brand-techcrunch/ Liquid Death, a water brand that started out in 2018 with a fun video to test the concept first, has gotten very serious about its prospects for growth. The Los Angeles-based company, which sells canned mountain water from the Alps that will “kill your thirst,” just landed $ 75 million in Series C funding led […]]]>

Liquid Death, a water brand that started out in 2018 with a fun video to test the concept first, has gotten very serious about its prospects for growth. The Los Angeles-based company, which sells canned mountain water from the Alps that will “kill your thirst,” just landed $ 75 million in Series C funding led by start-up studio Science, which helped when the company was launched and now has a “strong minority” position. (Says Science co-founder Mike Jones, “I wish we had more.”)

We spoke earlier today with the co-founder and CEO of Liquid Death, Mike Cessario, a West Coast creative agency turned entrepreneur, about the company’s growth. Apparently there is something to brag about. According to Cessario, Liquid Death is now distributed to more than 29,000 locations across the United States, including Whole Foods, Target, Safeway and 7-Eleven stores, and revenues reached nearly $ 45 million in the year. last, up from $ 3 million in 2019 when the company sold its first can.

He thinks there’s a lot of room to grow from here, including through the flavored waters that Liquid Death is starting to roll out with names that match the brand’s punk-metal ethos. His first three products? Berry It Alive, Severed Lime, and Mango Chainsaw.

Cessario has long attributed the company’s growth to its ominously funny wording, as well as its packaging, claiming that aluminum is more recyclable than plastic (although, of course, no single-use container is good for it. the environment).

Nonetheless, he’s especially proud of Liquid Death’s organic growth strategy, a strategy that has allowed the company to compete and even thrive in a world plagued by other water brands. Indeed, when asked how much Liquid Death spends on marketing compared to other drink brands, Cessario insisted there was no comparison.

“I don’t know what other water brands are spending, but we won’t have Coca-Cola or Pepsi-type budgets to spend. We don’t have $ 300 million to spend on something, so every piece of marketing we do has to be interesting or entertaining so people are spreading it organically.

Some of those marketing elements come together quickly, he said, in two weeks or less when “an idea comes out of nowhere.” Other times, a marketing campaign can last six months. Do a stunt last summer by Liquid Death and one of its famous few investors, Tony Hawk, who teamed up to sell 150 skateboards that had Hawk blood in ink in them. The decks sold out quickly, Cessario said, but making the decks, as well as lining up a phlebotomist who could “legally draw blood and was ready to be on camera” took some time, he said. laughing.

In an even more extreme gadget, Cessario had the face of an avid Liquid Death client tattooed on his arm.

As for how the company’s strategy is changing now that it has more products to offer, Cessario told us that the focus remains squarely on building a brand “that’s about making healthy drinks so fun.” or more fun than junk food and alcohol brands ”. Because his demographics are younger and masculine, and because “young children and most men have more of a sweeter palette of things,” Cessario observes, that means new drinks, which Cessario says are sweet. with agave nectar and contain only three grams of sugar and 20 calories per drink. (“We don’t take care of people who are obsessed with every last calorie,” he noted.)

In the meantime, there are obviously plenty of places in the United States that have yet to discover the brand. Highlighting a beverage industry metric called ACV (for the volume of all products) which represents the total annual sales volume of retailers, Cessario said Fiji’s water contained 90% ACV while Liquid Death barely approached 9% at the end of 2021.

A softer deal with Amazon may well increase that percentage. Specifically, Cessario said, Liquid Death recently adopted an important metric that Amazon uses to decide when to start wholesaling a product, which means Liquid Death is no longer charged for every instance of water it uses. sells through Amazon, but sells water directly to the e-commerce giant, which then sells the water directly to its customers at a discount – and has skyrocketed sales, Cessario said.

It’s important, he continued. “For many food and beverage brands, Amazon is often their biggest sales channel.”

Other investors in the new cycle of Liquid Death include Live Nation, PowerPlant Partners, Access Capital, and Nomad Ventures.

In total, Liquid Death has now raised $ 125 million.

He does not disclose his assessment.



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From saunas to flesh-eating insects: the big long reads of 2021 https://star-warz.net/from-saunas-to-flesh-eating-insects-the-big-long-reads-of-2021/ Sun, 02 Jan 2022 05:49:26 +0000 https://star-warz.net/from-saunas-to-flesh-eating-insects-the-big-long-reads-of-2021/ The year started with bots and ended with sessions – well, it did on the Insights desktop anyway. The long-running series of The Conversation is all about variety, and that’s certainly what 2021 has brought. Our authors have researched the world on a wide variety of topics. Whether they’re experts on flesh-eating beetles or climate […]]]>

The year started with bots and ended with sessions – well, it did on the Insights desktop anyway. The long-running series of The Conversation is all about variety, and that’s certainly what 2021 has brought.

Our authors have researched the world on a wide variety of topics. Whether they’re experts on flesh-eating beetles or climate change, anthropologists studying loneliness or historians uncovering the hidden tales that have shaped our present, they all have one thing in common: they know how to tell a story.

Some took us on the author’s intensely personal research journey and reflected the suffering COVID caused in 2021.

Others were surprising and hopeful, not to mention the intricate details and extensive research. Here are some of our personal highlights.

Historian of medical science, Matthew Eddy, has told the incredible story of James McCune Smith – the first known African-American physician to be published in a British medical journal and an indomitable abolitionist. Eddy’s story traces McCune Smith’s move from New York to Glasgow where he studied medicine and his efforts to expose harmful drug trials conducted by a senior white professor who was experimenting on vulnerable women. The play highlights a very important, but little-known event in British history.

It is difficult for many people to imagine what life will be like in old age. But one of the biggest worries about aging is whether or not we’ll have someone by our side to help us through these difficult years. COVID-19 and the lockdown have brought the long-standing issue of loneliness and isolation in the lives of older people back into the public consciousness. A new study has looked at what this type of isolation really is.

The Loneliness Project – an in-depth, large-scale exploration of how older people experience loneliness and what it means to them – generated over 130 hours of conversation. These honest and moving discussions were moderated by researchers Sam Carr and Chao Fang.

They found that loss, physical deterioration, biographical pain and regret all engender a unique sense of disconnection from the world. As Sam says, “Loneliness later in life runs deep – much deeper than you think.” In 2009-10, James Cummings spent 12 months studying Mandarin Chinese in Hainan and made friends in local gay communities. Inspired by these experiences, he spent eight years researching gay men in the area and, in 2018, completed a doctorate. thesis exploring the life of homosexuals in Hainan. He wanted to discover how the lives of homosexuals are lived on the fringes of global LGBT politics and activism, far from cities imagined as cosmopolitan centers of modernity.

Hainan is located in the Gulf of Tonkin, 30 km off the southern coast of mainland China. The region has historically sat on the fringes of the nation, long imagined as an isolated tropical wasteland of little economic or cultural value.

His revealing work explores how gay men claim spaces and build communities in their secret worlds.

2021 was also a year dominated by the climate crisis. There have been roaring fires from Canada to California to Greece, devastating flooding in Germany and China, and all the while greenhouse gas emissions have risen after the blow from the closures. of 2020. November saw the 26th UN climate change summit, COP26, which yielded mixed results and a lot of hot air on so-called “net zero” policies.

Net-zero, it seems, has become the litmus test for gauging how seriously a country (or business or person) is tackling the uncertain and damaging consequences of global warming. But concerns are growing that net zero itself is not fit for purpose. This is the claim made by three top climatologists in an article we published last April in collaboration with the editors of Apple News.

In the authors’ view, there is a dangerous problem with the concept at the heart of global climate policy. These scientists – including a former chairman of the Intergovernmental Panel on Climate Change – argued that for decades the concept of net zero has held back effective action and even encouraged the burning of fossil fuels. And many believe it continues to do so.

For something a little less tirelessly depressing, immerse yourself in the world of “wireheading”. It refers to a kind of behavioral loop in which stereotypical drug addicts and RNs get stuck, where the reward is sought at the expense of other goals. This phenomenon is quickly becoming a hot topic in the machine learning community and those concerned with AI security.

The story was written by two experts – one with a background in computational neuroscience and the other a historian. It’s an exciting read covering the hunt for the brain’s pleasure center, the cocaine rat experiments, video game fears, and an AI-driven future.

And maybe my favorite story of the year – and one I’ll take to heart over the Christmas season – is a story about the health benefits of saunas and hot tubs. It turns out that bathing regularly in hot water or in an even warmer room can cause some of the same physiological reactions as going for a run. Let’s drink to that!

(This story was not edited by Devdiscourse staff and is auto-generated from a syndicated feed.)


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Evolutionary Scientists Debunk Darwinian Spicy Food Theory https://star-warz.net/evolutionary-scientists-debunk-darwinian-spicy-food-theory/ Fri, 31 Dec 2021 14:00:25 +0000 https://star-warz.net/evolutionary-scientists-debunk-darwinian-spicy-food-theory/ When we eat spicy food – a pork enchilada, say, or maybe a Thai papaya salad – we usually experience one of two reactions (beyond thinking it’s delicious): the first is to drink a lot of ‘water ; the second is to add more spice. The tendency to go big or go home with the […]]]>

When we eat spicy food – a pork enchilada, say, or maybe a Thai papaya salad – we usually experience one of two reactions (beyond thinking it’s delicious): the first is to drink a lot of ‘water ; the second is to add more spice. The tendency to go big or go home with the spices is not only a hallmark of Asian and Latin American cuisine, it is also seen as evidence of a theory called Darwinian gastronomy. The point is, all of this belief could actually be proof of something else: the Western Eurocentric bias that limits good science.

REVERSE countdown the 20 scientific discoveries that made us say “WTF” in 2021. It’s # 1. See the full list here.

Discovery – In a study published earlier this year in the journal Nature Human Behavior, a team of researchers set out to challenge an idea central to Darwinian gastronomy: by eating spicy foods in environments where foodborne illness is common (i.e. in Latin America and Asia), humans benefit biologically.

The spicy cuisines of Central and South America and Asia had nurtured this concept – a long-held assumption among scientists is that diets high in certain spices have antimicrobial benefits and protect eaters from disease.

Thus, the researchers analyzed 33,750 recipes from 70 kitchens, with 93 different spices. Hotter countries with higher rates of foodborne illness tended to have spicier cuisines, but in the end, the researchers found absolutely no credible evidence to suggest that spicy foods offered any benefit. antimicrobial.

Lindell Bromham, the study’s first author and professor of ecology and evolution at Australian National University, put it bluntly in a statement at the time: the hottest, but our analysis provides no clear reason for primarily cultural adaptation to reduce the risk of infection from food.

Why is this important – Critically, this study is a demonstration of how biases can affect scientific theory: At first glance, antimicrobial theory has legs: Sure, people living in places where the risk of infection from food is higher would do everything possible to prevent disease. Darwinian gastronomy suggests that what we love to eat stems in part from how our bodies have adapted to their surroundings – but this study suggests the opposite when it comes to spice theory.

Ultimately, the study offers a different insight: Scientists may reverse engineer theories based on correlations rather than an underlying cause due to their own biases and beliefs.

Western prejudices about spice-laden foods – like the nutmeg seen here going to your cellar – may have clouded our investigation into their true benefits.danm / Moment / Getty Images

How they did it – Broham and his team examined the ingredients of tens of thousands of recipes. They calculated the average and median spice usage per recipe and combined this data with information on a myriad of socio-economic and environmental factors gleaned from different regions of the world.

Oddly enough, the researchers found plenty of correlations in the data they could use to explain why spicy food is apparently preferable in warmer countries and regions – but when they looked closer and tried to validate a link, that -It collapsed.

In a revealing analysis, the team points out that the number of road accidents more accurately predicts the spiciness of local cuisine than the prevalence of foodborne illness.

And after – This study debunks a popular myth about spicy food. But it can help inform the path in which we interpret scientific theories, information and findings. Science as a whole suffers from a historical Western bias that can lead to narrow data sets, limited analysis, and cultural narratives eclipsing good science. In other words, even if something looks right to you, check yourself before you invest.

It may take a moment to figure out, but you can still contemplate it over a bowl of goat vindaloo or dan-dan noodles.

REVERSE countdown the 20 scientific discoveries that made us say “WTF” in 2021. It’s # 1. Read the original story here.


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Opinion on the homicide in the death of a teenager from Kan. is not a legal decision https://star-warz.net/opinion-on-the-homicide-in-the-death-of-a-teenager-from-kan-is-not-a-legal-decision/ Wed, 29 Dec 2021 22:05:28 +0000 https://star-warz.net/opinion-on-the-homicide-in-the-death-of-a-teenager-from-kan-is-not-a-legal-decision/ Cedric Lofton-photo GoFundMe SEDGWICK COUNTY – An autopsy report indicates the death of a black youth as a result of a physical fight with staff at a Kansas juvenile center was homicide. The autopsy report released on Monday contradicts an earlier preliminary finding that Cedric Lofton, 17, did not sustain any life-threatening injuries. On Tuesday, […]]]>
Cedric Lofton-photo GoFundMe

SEDGWICK COUNTY – An autopsy report indicates the death of a black youth as a result of a physical fight with staff at a Kansas juvenile center was homicide. The autopsy report released on Monday contradicts an earlier preliminary finding that Cedric Lofton, 17, did not sustain any life-threatening injuries.

On Tuesday, December 28, attorneys and investigative staff from the Sedgwick County Attorney’s Office met with officers from the Kansas Bureau of Investigations and detectives from the Sedgwick County Sheriff’s Office to discuss the investigation into Cedric Lofton’s death, according to a statement from District Attorney Marc Bennett.

Courtesy of Sedgwick County Regional Forensic Science Center
Courtesy of Sedgwick County Regional Forensic Science Center

This was the sixth time that members of the district attorney’s office had met investigators from one or both agencies since September. The district attorney is reviewing more than 90 pieces of evidence, including interviews, transcripts, surveillance footage and axon (body camera) videos provided by investigators throughout the investigation.

Contrary to numerous public comments since the publication of the autopsy report prepared by the Sedgwick County Regional Forensic Science Center, the determination that the mode of death was “homicide” does not reflect a legal determination on the part of the pathologist regarding viability. of the criminal offense. charges.

Whether or not criminal charges can be laid is a separate legal decision that must be made by the district attorney’s office based on the laws of the state of Kansas and evidence gathered by the forces of the United States. order.

“A Guide for Medical Examiners” published by the National Association of Medical Examiners, recognizes that there are generally 5 descriptors used in autopsy reports when listing a mode of death: (1) Natural; (2) Accidents; (3) suicide; (4) Homicide; and (5) Undetermined. The term “homicide” reflects a determination that a willful (non-accidental) act was committed by someone other than the deceased and contributed to the death of the deceased. The finding does not reflect a compelling legal finding that the elements of murder or manslaughter are present.

The guide explains,

An assessment of “intent” relates to the classification of the mode of death: it necessarily underlies the quasi-judicial liability flowing from the enabling statute in the relevant jurisdiction of the certifier of death. However, the legal point of view of intention may differ from the point of view of the death investigator. It is sometimes terribly difficult, and sometimes impossible, for an impartial investigator to infer the intention of a victim or “aggressor”. Intention is also much more apparent in some cases than in others. For this reason, the notion of “voluntary acts” or “volition” can be useful. In general, if the death of a person results from the “hands of another” who committed a willful act harmful to the victim, the death may be considered homicide from the perspective of the death investigation. . . Although there was no intention to kill the victim, the victim died as a result of the harmful, intentional and willful act of another person. Thus, the mode of death can be qualified as homicide because of the intentional or voluntary act, and not because there was an intention to kill.

The guide further recognizes,

Deaths due to law enforcement-induced restraint or strangulation or other control measures can be classified as homicide. In such cases, there may be no intention to kill, but death results from one or more intentional, willful and potentially harmful acts directed against the deceased person (without their consent, of course). In addition, the classification of homicides has some value in reducing public perception that a “cover-up” is being carried out by the death investigation agency.

While the identification of a cause of death set out in the autopsy report is a necessary step in the investigative process, the legal determination of the viability of criminal charges requires a separate legal review. This work is ongoing.

In the absence of unforeseen circumstances, the district attorney’s office plans to complete the examination within the next 10 to 15 working days. The public will be notified at that time.


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CBR’s 100 Best Comics of 2021: 100-76 https://star-warz.net/cbrs-100-best-comics-of-2021-100-76/ Mon, 27 Dec 2021 23:07:32 +0000 https://star-warz.net/cbrs-100-best-comics-of-2021-100-76/ After a short five year hiatus, we are back with a long CBR tradition. At the end of the year, we polled the many CBR staff who make this site so awesome and asked them for their ranking of the best comics of the year. Every publisher releasing new comics in English, regardless of genre […]]]>

After a short five year hiatus, we are back with a long CBR tradition. At the end of the year, we polled the many CBR staff who make this site so awesome and asked them for their ranking of the best comics of the year. Every publisher releasing new comics in English, regardless of genre or format, was fair game; each individual list is then taken into account to determine the overall Top 100 that will be unveiled on CBR during that week.

Today we begin to unveil the list with entries # 100 through 76, with the countdown continuing each day this week. Here is the schedule (all Eastern hours): Tuesday, 12/28, 3 p.m .: Top 75-51; Wednesday 12/29/3 p.m .: Top 50-26; Thursday 12/30, 3 p.m .: Top 25-11; Friday 12/31/3 p.m .: Top 10; Saturday 1/1, 9 a.m .: Master list.


Start going through the list below, and if you are feeling so moved, take Twitter and (politely) discuss your thoughts using the hashtag # CBRTop100.

100. Checkmate


Written by: Brian Michael Bendis

Illustrations by: Alex Maleev, David Stewart and Lee Loughridge

Publisher: DC

This thrilling spy series continued the story of The Event: Leviathan by starring a motley team of DC heroes trying to save the world from the evil clutches of the massive criminal organization, Leviathan.

99. Red room


Written by: Ed Piskor

Art by: Ed Piskor

Publisher: Fantagraphics

A twisted look at a possible evolution of the Internet where the dark web is filled with “red rooms” where torture and murder are committed to the delight of a sick public. Is it too far to be stopped?


98. The honor of the scout


Written by: David Pepose

Art by: Luca Casalanguida and Matt Milla

Publisher: Aftershock Comics

In this post-apocalyptic world lives a group that still lives by a code … the Ranger Scout code. But as the story goes, if you build on a faulty foundation everything will fall apart, and when one of the greatest scouts uncovers the rot at the heart of the movement, what will she do to make things right?

97. Dead Dog Bite


Written by: Tyler Boss

Creation: Tyler Boss

This mysterious and dense comic rewards multiple readings with the level of detail that Boss puts into both the characters and the world they inhabit, a world tinged with a bit of nostalgia, a lot of weird humor and a lot slightly disturbing.


Publisher: Dark Horse Comics

96. Sonic the Hedgehog


Written by: Ian Flynn, Evan Stanley

Creation: Tracy Yardley, Evan Stanley, Matt Froese and Matt Herms

Publisher: IDW

Evan Stanley has joined Ian Flynn to give the regular Sonic series two compelling storytelling writers set in the SEGAverse as the book prepares to hit the 50th issue mark.

95. MODOK head games


Written by: Jordan Blum and Patton Oswalt

Art by: Scott Hepburn and Carlos Lopez

Publisher: Marvel

This gripping miniseries manages to force you to truly feel MODOK as we travel to the nastiest recesses of its mind… or Butterville, Ohio. It’s hard to say which one is the worst.


94. Stargirl: Spring Break Special


Written by: Geoff Johns

Art by: Todd Nauck and Hi-Fi

Publisher: DC

The Stargirl creator has returned to the now TV star to tell a delightful new story embracing the best aspects of the DC Universe.

93. High school family


Written by: Ryo Nakama

Illustration by: Ryo Nakama

Publisher: Viz

High School Family begins when a young man learns that his father, mother, younger sister, and cat will all go to high school with him. Although this is primarily a comic manga, the story often ends up in heartfelt, thoughtful places where the characters grow up between each joke. – Christian Garnett, anime list writer

92. Gamma flight


Written by: Al Ewing and Crystal Frasier


Art by: Lan Medina and Antonio Fabela

Publisher: Marvel

This deliciously fun spinoff of Immortal Hulk has embraced the best aspects of the Marvel Universe with its fun and engaging spotlight on excellent but underused characters.

91. Mighty Morphin ‘


Written by: Ryan Parrott

Art by: Marco Renna, Dan Mora, Walter Baiamonte, Katia Ranalli, Sara Antonellini, Raul Angulo and Jose Enrique Fernandez

Publisher: BOUM!

BOOM! really gave readers the best of both worlds when he split the two Power Rangers books under the same author, as the strong sense of continuity makes it seem like while the two books tell very different stories, they share still a basic sense of the general Power Ranger universe.


90. Way of X


Written by: Si Spurrier

Art by: Bob Quinn and Java Tartaglia

Publisher: Marvel

What started as Nightcrawler’s attempt to reconcile the kind of religion that was building around the X-Men slowly turned into a corruption investigation that had a massive reveal that could change the world of the X-Men from significantly.

89. Mouth-sized Archie


Written by: Ron Cacace

Creation: Vincent Lovallo

Publisher: Archie Comics

This charming new take on Archie’s classic gag strip concept brings jokes into the modern era, but retains the classic joke styles, which never went out of fashion.

88. Ninjak


Written by: Jeff Parker

Art by: Javier Pulido (then Beni Lobel and Andrew Dalhouse)


Publisher: Vaillant

This series took an exciting and artistically fascinating new take on the proven spy concept with a quirky adventure series that made better use of the comic book format than 99% of the comics on the market today.

87. Dinos and comics


Written by: Jacques

Art by: K

Publisher: Dinosandcomics.com

These candid mental health life reviews have captured the hearts and minds of millions of people on the Internet.

86. Excalibur


Written by: Tini Howard

Art by: Marcus To and Erick Arciniega

Publisher: Marvel

Excalibur continues to spin a dozen different plates at once, balancing the interpersonal conflicts of the team itself (as Psylocke and Betsy Braddock are always going to have problems) with the highly political maneuvers of England and the ‘Other world.


85. Batman: Urban Legends


Written By: Far too many to list them all, but the DC website has them all here.

Art by: Far too many to list them all, but the DC website has them all here.

Publisher: DC

This anthology spotlighting various members of the Batman Family is perhaps best known in 2021 for the story arc where Tim Drake realized he was bisexual.

84. The Chilling Adventures of Sabrina


Written by: Roberto Aguirre-Sacasa

Creation: Robert Hack

Publisher: Archie Comics

Horror fans got a special treat (no tricks) this year with the return of this delightfully twisted riff on the classic Sabrina the Teenage Witch character that had a major influence on the recent hit Netflix series.


83. Aquaman: Becoming


Written by: Brandon Thomas

Creation: Diego Olortegui, Skylar Patridge, Scott Koblish, Wade von Grawbadger and Adriano Lucas

Publisher: DC

Jackson Hyde embarks on a journey of redemption after his life has collapsed around him and hopefully he will eventually clear his name and earn the name Aquaman using everything he has learned during his life. life so far.

82. Dr Pierre


Written by: Riichir Inagaki

Art by: Boichi

Publisher: Viz

Things keep getting crazier and crazier in the wild world of Dr. Stone, as the scientific realms of Senku and Dr. Xenu are at odds and it will likely take all the “power of science” that Senku and his friends can muster. to keep Senku from being killed, not to mention defeating Dr. Xenu in this quirky adventure set in the distant future.


81. Power Rangers


Written by: Ryan Parrott and Rachel Wagner

Art by: Francesco Mortarino, Simone Ragazzoni, Moises Hildalgo, Simona Di Gianfelice, Gilbey Ibarra, Raul Angulo, Jose Enrique Fernandez, Igor Monti and Sabrina Del Grosso.

Publisher: BOUM!

Have the two main BOOM! The Power Rangers series shares a writer who particularly paid off at the end of the year, as the two series came together in an exciting crossover adventure.

80. Detective Comics


Written by: Mariko Tamaki

Illustrations by: Dan Mora, Viktor Bogdanovic, Daniel Henriques and Jordie Bellaire

Publisher: DC

The introduction of a big new villain in Mr. Worth and a fresh take on Gotham City made this Police comics run really does stand out in 2021, especially with the series of compelling save stories.


79. one piece


Written by: Eiichiro Oda

Art by: Eiichiro Oda and Gege Akutami

Publisher: Viz

Most English versions of A piece in 2021 followed a flashback to Kozuki Oden’s early days on the seas, twenty years before the series’ main storyline, but these adventures gave us new perspectives on the character of Oden while also introducing a number information on the overall history of the series.

78. Katie the catsitter


Written By: Colleen AF Venable

Art by: Stéphanie Yue

Publisher: Random House Children’s Books

This delightful intro to Katie the Catsitter sees a preteen sit in a woman’s apartment who may or may not be a supervillain, and her cats may or may not have various superpowers. When things are going well, can Katie be trusted to work with the cats to save their owner? Yes, yes she can, but it’s always interesting how she gets to this point and HOW they do it!


77. We have demons


Written by: Scott Snyder

Illustrations by: Greg Capullo, Jonathan Glapion and Dave McCaig

Publisher: ComiXology Originals

Reuniting the classic Batman and Death Metal creative team delivered a delightfully fun new adventure of demons and demon hunters while spending a lot of time building the vast lore of this new world they’ve created. However, it never gets boring because the information you learn is exciting because you want to know more about it.

76. UltraMega


Written by: James Harren

Art by: James Harren and David Stewart

Publisher: Image Comics

This series is both a loving tribute to kaiju stories and a bit of a satire on the concept while upping it up by around 1000% in each issue. You never know what’s going to happen next, in the best possible way.


Check back with CBR on Tuesday to learn more about the Top 100!

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